Oncology & Cancer

Gene discovery may explain female melanoma survival advantage

Centenary Institute scientists have discovered that genes on the X chromosome may be key to the improved survival rates of females with melanoma–as compared to their male counterparts. The findings could ultimately lead ...

Medical research

Molecules in urine allow doctors to monitor skin cancer

What if you could simply provide a urine sample rather than undergo a painful surgical procedure to find out if your cancer was responding to treatment? It may seem too good to be true, but researchers at Pavol Jozef Šafárik ...

Medications

Pembrolizumab use supported in advanced melanoma

(HealthDay)—Use of pembrolizumab is supported among patients with advanced melanoma, regardless of BRAF V600E/K mutation status or prior receipt of a BRAF inhibitor (BRAFi) with or without MEK inhibitor (MEKi) therapy, ...

Medical research

Scientists grew cancers to develop a melanoma research tool

A nationwide group of researchers from the Maurice Wilkins Center (MWC) have recently reported a detailed characterisation of one of the largest melanoma cell line panels ever developed that makes this a resource for research ...

Oncology & Cancer

A helping hand for cancer immunotherapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...

Oncology & Cancer

Scientists identify new target for melanoma immunotherapy

QIMR Berghofer research has found a new reason why some melanoma patients do not respond well to immunotherapy—a discovery that could lead to better-tailored treatments for the potentially deadly cancer.

Oncology & Cancer

Steep rise in skin cancer since 1960s

The risk of developing more than one skin melanoma over a ten-year period has seen a ten-fold increase in Sweden since the 1960s, a new study by researchers at Karolinska Institutet and Lund University published in the Journal ...

page 1 from 78

Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

This text uses material from Wikipedia licensed under CC BY-SA