(HealthDay) -- For patients with metastatic melanoma with activating mutations in serine-threonine protein kinase B-RAF (BRAF), treatment with the oral selective MEK inhibitor trametinib is associated with improved progression-free ...
Jun 5, 2012
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Australian researchers said Wednesday they have developed a blood test for melanoma in its early stages, calling it a "world first" breakthrough that could save many lives.
Jul 18, 2018
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Researchers have shown for the first time that a form of artificial intelligence or machine learning known as a deep learning convolutional neural network (CNN) is better than experienced dermatologists at detecting skin ...
May 28, 2018
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When malignant melanoma metastasizes to the brain, it is a death sentence for most patients. Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and interactions ...
Jul 25, 2016
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Cancer immunotherapies and targeted therapy have revolutionized how clinicians take care of patients with advanced skin cancer and have led to long lasting treatment responses for many of them. However, little is known about ...
Jul 12, 2018
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In a small patch of skin no bigger than an inch, there are millions of cells all performing duties, like protecting us from bacteria and sensing temperature. A portion of them are melanocytes, a type of cell dedicated to ...
Aug 4, 2022
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In a newly published study, researchers at Dartmouth's Norris Cotton Cancer Center find that unique immune cells, called resident memory T cells, do an outstanding job of preventing melanoma. The work began with the question ...
Apr 14, 2017
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Melanoma kills more than 1,700 Australians every year, which is more than the national road toll. But the good news is it's treatable if caught early enough. And a new blood test might be able to help with faster and easier ...
Jul 18, 2018
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Learning your ABCs can alert you to changes in moles that could signal melanoma—the most serious type of skin cancer.
May 13, 2022
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Researchers say a combination of new treatments can stop the world's deadliest form of skin cancer—melanoma—in its tracks and halt its spread to other organs.
Sep 11, 2017
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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
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