Motor Neurone Disease

First step toward CRISPR cure of Lou Gehrig's disease

University of California, Berkeley scientists have for the first time used CRISPR-Cas9 gene editing to disable a defective gene that causes amyotrophic lateral sclerosis, or Lou Gehrig's disease, in mice, extending their ...

Dec 20, 2017
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A pathogenic mechanism in motoneuron disease

Motor neurons are the nerves that send impulses to the muscles to generate movement. Damage of these neurons can cause very diverse diseases, for example spinal muscular atrophy in children or adult amyotrophic lateral sclerosis.

Nov 02, 2017
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The motor neurone diseases (or motor neuron diseases) (MND) are a group of neurological disorders that selectively affect motor neurones, the cells that control voluntary muscle activity including speaking, walking, breathing, swallowing and general movement of the body. They are generally progressive in nature, and can cause progressive disability and death. The drug riluzole can slow progression slightly; apart from this the medical care is supportive. The condition was first described in full by the French neurologist Jean-Martin Charcot in 1869.

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