Medical research

Molecular 'scaffold' could hold key to new dementia treatments

Researchers at King's College London have discovered how a molecular 'scaffold' which allows key parts of cells to interact, comes apart in dementia and motor neuron disease, revealing a potential new target for drug discovery.

Neuroscience

Research into axon degeneration hits a nerve

(Medical Xpress)—University of Queensland (UQ) researchers have made a significant discovery that could one day halt a number of neurodegenerative diseases.

Genetics

New gene variant discovered for ALS

(Medical Xpress)—Research led by King's College London has identified a new genetic variant, located on chromosome 17, associated with sporadic amyotrophic lateral sclerosis (ALS) – the most common form of motor neurone ...

Diseases, Conditions, Syndromes

Stem cell discovery gives insight into motor neurone disease

A discovery using stem cells from a patient with motor neurone disease could help research into treatments for the condition. The study used a patient's skin cells to create motor neurons - nerve cells that control muscle ...

Medical research

Stay-at-home transcription factor prevents neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...

Neuroscience

Discovering how the brain ages

Researchers at Newcastle University have revealed the mechanism by which neurons, the nerve cells in the brain and other parts of the body, age. The research, published today in Aging Cell, opens up new avenues of understanding ...

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