Myocardial Infarction

Heart attack shown to be 'systemic condition'

An acute heart attack should not be viewed in isolation – myocardial infarction is a "systemic" condition with an impact upon the whole body and engenders responses in other organs, such as liver and spleen. That is the ...

Jun 28, 2017
popularity2 comments 0

Lutein may suppress inflammation

Lutein, a nutrient found in several highly coloured vegetables and fruits, can suppress inflammation, according to a new study by researchers at Linköping University, Sweden. The results, published in Atherosclerosis, suggest ...

Jul 05, 2017
popularity2 comments 0

Tracking the mechanisms of artery formation

Arteriogenesis is a critical event - not only during development but also in adult life. Cardiovascular life-threatening events, triggered by disease, could be overcome by alternatives to existing therapies, for example by ...

Jul 17, 2017
popularity62 comments 0

Coronary CT angiography ups prediction of MACE in T2DM

(HealthDay)—For asymptomatic patients with type 2 diabetes, the addition of coronary computed tomography angiography (CCTA)-detected obstructive coronary artery disease (CAD) improves prediction of major adverse cardiovascular ...

Jul 10, 2017
popularity0 comments 0

Timing of mutation determines the outcome

A single genetic mutation can lead to completely different diseases, depending on the time and location at which the mutation occurs. This finding emerged from the PhD study conducted by Rocio Acuña-Hidalgo of Radboudumc. ...

Jun 30, 2017
popularity59 comments 0

Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, results from the interruption of blood supply to a part of the heart, causing heart cells to die. This is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque, which is an unstable collection of lipids (cholesterol and fatty acids) and white blood cells (especially macrophages) in the wall of an artery. The resulting ischemia (restriction in blood supply) and ensuing oxygen shortage, if left untreated for a sufficient period of time, can cause damage or death (infarction) of heart muscle tissue (myocardium).

Classical symptoms of acute myocardial infarction include sudden chest pain (typically radiating to the left arm or left side of the neck), shortness of breath, nausea, vomiting, palpitations, sweating, and anxiety (often described as a sense of impending doom). Women may experience fewer typical symptoms than men, most commonly shortness of breath, weakness, a feeling of indigestion, and fatigue. Approximately one-quarter of all myocardial infarctions are "silent", that is without chest pain or other symptoms.

Among the diagnostic tests available to detect heart muscle damage are an electrocardiogram (ECG), echocardiography, cardiac MRI and various blood tests. The most often used blood markers are the creatine kinase-MB (CK-MB) fraction and the troponin levels. Immediate treatment for suspected acute myocardial infarction includes oxygen, aspirin, and sublingual nitroglycerin.

Most cases of STEMI (ST elevation MI) are treated with thrombolysis or percutaneous coronary intervention (PCI). NSTEMI (non-ST elevation MI) should be managed with medication, although PCI is often performed during hospital admission. In people who have multiple blockages and who are relatively stable, or in a few emergency cases, bypass surgery may be an option, especially in diabetics.

Heart attacks are the leading cause of death for both men and women worldwide. Important risk factors are previous cardiovascular disease, older age, tobacco smoking, high blood levels of certain lipids (triglycerides, low-density lipoprotein) and low levels of high density lipoprotein (HDL), diabetes, high blood pressure, obesity, chronic kidney disease, heart failure, excessive alcohol consumption, the abuse of certain drugs (such as cocaine and methamphetamine), and chronic high stress levels.

This text uses material from Wikipedia licensed under CC BY-SA

Latest Spotlight News

Concerns that sleep apnea could impact healthspan

The number of people with obstructive sleep apnea has steadily increased over the past two decades. The disorder, which causes a person to briefly stop breathing when asleep, affects over 100 million people globally and is ...

DREAMers at greater risk for mental health distress

Immigrants who came to the United States illegally as small children and who meet the requirements of the Development Relief and Education for Alien Minors Act, more commonly known as DREAMers, are at risk for mental health ...

Sugar not so sweet for mental health

Sugar may be bad not only for your teeth and your waistline, but also your mental health, claimed a study Thursday that was met with scepticism by other experts.

Cancer-death button gets jammed by gut bacterium

Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes. They found that Fusobacterium nucleatum in the gut can stop chemotherapy ...