Cardiology

Risk of major heart complications up shortly following stroke

(HealthDay)—Ischemic stroke is independently associated with increased risk of incident poststroke major adverse cardiovascular events (MACE) in both men and women, according to a study published in the February issue of ...

Cardiology

Declines in heart attacks greater among men than women

In a study published in the American Heart Association scientific journal Circulation, Kaiser Permanente research scientists report a steady decline in heart attacks for both men and women enrolled in the health system from ...

Medications

Amlodipine better BP drug for lower long-term risk for gout

(HealthDay)—The antihypertensive medication amlodipine is associated with a lower risk for gout compared with other antihypertensive agents, according to a study published online Jan. 20 in the Journal of Hypertension.

Cardiology

Model predicts six-month post-AMI mortality for older adults

(HealthDay)—A newly developed model has good discriminatory ability for six-month post-acute myocardial infarction (AMI) mortality, according to a study published online Dec. 10 in the Annals of Internal Medicine.

page 1 from 23

Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, results from the interruption of blood supply to a part of the heart, causing heart cells to die. This is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque, which is an unstable collection of lipids (cholesterol and fatty acids) and white blood cells (especially macrophages) in the wall of an artery. The resulting ischemia (restriction in blood supply) and ensuing oxygen shortage, if left untreated for a sufficient period of time, can cause damage or death (infarction) of heart muscle tissue (myocardium).

Classical symptoms of acute myocardial infarction include sudden chest pain (typically radiating to the left arm or left side of the neck), shortness of breath, nausea, vomiting, palpitations, sweating, and anxiety (often described as a sense of impending doom). Women may experience fewer typical symptoms than men, most commonly shortness of breath, weakness, a feeling of indigestion, and fatigue. Approximately one-quarter of all myocardial infarctions are "silent", that is without chest pain or other symptoms.

Among the diagnostic tests available to detect heart muscle damage are an electrocardiogram (ECG), echocardiography, cardiac MRI and various blood tests. The most often used blood markers are the creatine kinase-MB (CK-MB) fraction and the troponin levels. Immediate treatment for suspected acute myocardial infarction includes oxygen, aspirin, and sublingual nitroglycerin.

Most cases of STEMI (ST elevation MI) are treated with thrombolysis or percutaneous coronary intervention (PCI). NSTEMI (non-ST elevation MI) should be managed with medication, although PCI is often performed during hospital admission. In people who have multiple blockages and who are relatively stable, or in a few emergency cases, bypass surgery may be an option, especially in diabetics.

Heart attacks are the leading cause of death for both men and women worldwide. Important risk factors are previous cardiovascular disease, older age, tobacco smoking, high blood levels of certain lipids (triglycerides, low-density lipoprotein) and low levels of high density lipoprotein (HDL), diabetes, high blood pressure, obesity, chronic kidney disease, heart failure, excessive alcohol consumption, the abuse of certain drugs (such as cocaine and methamphetamine), and chronic high stress levels.

This text uses material from Wikipedia licensed under CC BY-SA