Research led by Michael Lan, Ph.D., Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and ...
Apr 12, 2019
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Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania analyzed the largest cohort to date of pediatric patients with high-risk neuroblastoma treated ...
Apr 9, 2019
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Anyone who has ever studied the molecular basis of breast cancer will probably have heard of BRCA1, a protein that protects the cells of breast tissue against cancer. Surprisingly, this protein can also have the opposite ...
Mar 20, 2019
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Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia (CHOP) have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, ...
Mar 13, 2019
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The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumour cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer.
Jan 31, 2019
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A very large team of researchers, mostly from multiple institutions across Germany, has found what might be a better way to treat patients with neuroblastoma, a type of cancer. In their paper published in the journal Science, ...
Researchers investigating new treatments for neuroblastoma—one of the most common childhood cancers—have found that a combination of two drugs made tumours disappear in mice, making it more effective than any other drugs ...
Nov 15, 2018
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Neuroblastoma, a disease of immature nerve cells, is the most common solid tumor cancer occurring in children. About 700 new cases are diagnosed in the U.S. each year with approximately half of these children developing high-risk ...
Oct 4, 2018
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A phase 2 clinical trial has found that combining a novel compound called alisertib with chemotherapy has anti-tumor activity in children with high-risk, relapsed neuroblastoma. The New Approaches to Neuroblastoma Therapy ...
Oct 1, 2018
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Dr. Kenneth Alexander was driving home one day last year when he thought of the idea: What if the Zika virus could be used to kill a childhood cancer called neuroblastoma?
Jul 25, 2018
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