Neuroscience

Discovery illuminates how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form within and kill brain cells ...

Parkinson's & Movement disorders

Parkinson's disease mutation misdirects iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...

Neuroscience

NFL players face 4 times the odds of ALS

NFL players are four times more likely to die of Lou Gehrig's disease (ALS) than other people, new research finds, adding to known links between football-related head injuries and brain diseases, including Alzheimer's, Parkinson's ...

Neuroscience

Study reveals journey of immune cells in developing zebrafish

Microglia, the immune cells of the brain, form the first line of defense against neurodegenerative diseases and traumatic brain injuries. They maintain brain homeostasis, the stable condition necessary for survival, by acting ...

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