Through a structural and functional approach, researchers from the Icahn School of Medicine at Mount Sinai and Stanford University Medical Center identified physical binding sites for cholesterol in the brain's G-protein-gated ...
Aug 24, 2021
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A recent experimental study shows how regular physical exercise modulates iron metabolism in both the brain and the muscles. The findings also help to better understand the benefits of exercise in Alzheimer's disease. The ...
Aug 23, 2021
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Neurodegenerative diseases—an umbrella term for a range of conditions affecting the neurons in the human brain—impact millions of people worldwide. The most common of these diseases are Alzheimer's and Parkinson's, with ...
Aug 23, 2021
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Researchers from Tokyo Medical and Dental University (TMDU), Takeda Pharmaceutical Co., Ltd. and Ionis Pharmaceuticals, USA, show that heteroduplex oligonucleotide drugs conjugated with cholesterol cross the blood–brain ...
Aug 12, 2021
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Researchers from Oregon Health & Science University have for the first time demonstrated it's possible to use a synthetic thyroid hormone to regulate a gene implicated in neurodegenerative diseases like Alzheimer's, Parkinson's ...
Aug 12, 2021
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Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43. The study, which will be published ...
Aug 4, 2021
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Parkinson's disease and Alzheimer's disease are neurodegenerative diseases whose progression cannot be stopped with the currently available drug therapies. Numerous new drug candidates have proved disappointing in clinical ...
Jul 29, 2021
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A new technique developed at Western University to visually iron out the wrinkles and folds in one region of the brain may provide researchers a more accurate picture to understand brain disorders.
Jul 27, 2021
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Adequate blood flow supplies the brain with oxygen and nutrients, but the oxygenation tends to fluctuate in a distinct, consistent manner. The root of this varied activity, though, is poorly understood.
Jul 15, 2021
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A new University of Arizona Health Sciences study found women on hormone therapy were up to 58% less likely to develop neurodegenerative diseases including Alzheimer's disease, and reduction of risk varied by type and route ...
Jul 12, 2021
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