Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9 in the open-access journal ...
10 hours ago
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Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer's. The research is published in the journal eLife.
Apr 22, 2024
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A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.
Apr 16, 2024
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Scientists at Sanford Burnham Prebys have demonstrated that vesicles traveling between cells in the brain carry more complete instructions for altering cellular function than previously thought.
Apr 9, 2024
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Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer's disease ...
Apr 5, 2024
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Clinicians often find limited success in treating patients with traumatic brain injury, a condition long linked to contact sports and military services. A new study, published in the journal Cell Stem Cell, may offer new ...
Apr 4, 2024
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A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in ...
Apr 4, 2024
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Amylyx Pharmaceuticals announced Thursday it was withdrawing its approved treatment against the deadly neurodegenerative disease ALS after clinical data found no evidence the drug worked.
Apr 4, 2024
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The world's most powerful MRI scanner has delivered its first images of human brains, reaching a new level of precision that is hoped will shed more light on our mysterious minds—and the illnesses that haunt them.
Apr 2, 2024
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Stressful experiences in midlife or during childhood may be associated with a higher risk of developing Alzheimer's disease and neuroinflammation, respectively. This is one of the conclusions of a study published in Annals ...
Apr 2, 2024
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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including Parkinson’s, Alzheimer’s, and Huntington’s occur as a result of neurodegenerative processes. As research progresses, many similarities appear which relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.
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