The protein TREM2, which in humans is encoded by the TREM2 gene, is known to play a crucial role in the growth and development of different types of immune cells, including microglia. Microglia are specialized immune cells ...
Past neuroscience research consistently found a link between deviations from the "normal" iron metabolism, also known as iron dysregulation, and different neurodegenerative diseases, including Parkinson's disease (PD) and ...
Past neuroscience studies have consistently demonstrated that the aging of the mammalian nervous system is liked with a decline in the volume and functioning of white matter, nerve fibers found in deep brain tissues. Although ...
New imaging of patients with Alzheimer's demonstrates how a telltale protein spreads throughout the brain based on the phenotype of the disease, i.e., whether the condition is dominated by forgetfulness, or atrophy in a specific ...
(Medical Xpress)—A recent perspective paper published in Science has raised some important, and timely, questions regarding neural diversity. The authors, from Columbia, MIT, and New York University, would simply like to ...
(Medical Xpress)—In the battle against aging and age-related neurological diseases such as Parkinson's and Alzheimer's, a key factor has long appeared to be the toxicity of proteins which tend to aggregate. Recently, scientists ...
Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechanisms are the subject of ongoing research and debate. When it comes to Huntington's disease, steadily accumulating evidence ...
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Sleep is known to play a key role in facilitating various physiological processes, while also contributing to the healthy functioning of the brain. Lack of sleep and poor sleep quality have been linked to various chronic ...
Researchers at the Scripps Research Institute, Florida, have developed a new method to counteract α-synuclein protein levels by targeting the mRNA that forms them. The strategy unlocks many research doors with potential ...
Research led by the Center for Biomedical Technology, Universidad Politécnica de Madrid, Spain, has compared the brains of superagers with those of normal cognitive aged abilities in a paper, "Brain structure and phenotypic ...
Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases including Parkinson’s, Alzheimer’s, and Huntington’s occur as a result of neurodegenerative processes. As research progresses, many similarities appear which relate these diseases to one another on a sub-cellular level. Discovering these similarities offers hope for therapeutic advances that could ameliorate many diseases simultaneously. There are many parallels between different neurodegenerative disorders including atypical protein assemblies as well as induced cell death. Neurodegeneration can be found in many different levels of neuronal circuitry ranging from molecular to systemic.
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