Medical research

Finding a way forward in the fight against prion disease

For much of her adult life Valerie Sim has been fascinated by a disease very few in the world can claim to even begin to understand. Sim is one of Canada's foremost authorities on prion disease—more commonly known as bovine ...

Medical research

Small loop in human prion protein prevents chronic wasting disease

Chronic wasting disease (CWD)—an infectious disease caused by prions—affects North American elk and deer, but has not been observed in humans. Using a mouse model that expresses an altered form of the normal human prion ...

Medical research

Researchers show environment can neutralize lethal proteins

Botching a few folds might transform an origami cow into a deer or sheep. When cellular proteins do the same, they can trigger fatal neurodegenerative diseases that turn the brains of these mammals into dysfunctional sponges.

Medical research

Scientists develop nasal test for human prion disease

A nasal brush test can rapidly and accurately diagnose Creutzfeldt-Jakob disease (CJD), an incurable and ultimately fatal neurodegenerative disorder, according to a study by National Institutes of Health (NIH) scientists ...

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