Medical research
Brain infection study reveals how disease spreads from gut
Diagnosis of deadly brain conditions could be helped by new research that shows how infectious proteins that cause the disease spread.
Aug 4, 2015
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28
Prion Diseases
Medical research
How prions kill neurons: New culture system shows early toxicity to dendritic spines
Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. A study published on May 26, 2016 in PLOS Pathogens describes a system ...
May 26, 2016
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122
Medical research
Screen finds an antidepressant, other drugs, opens possibility of treating brain-wasting mad cow disease
In a new study NYU School of Medicine researchers report that they have found several chemical compounds, including an antidepressant, that have powerful effects against brain-destroying prion infections in mice, opening ...
Sep 14, 2011
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0
Medical research
Scientists develop nasal test for human prion disease
A nasal brush test can rapidly and accurately diagnose Creutzfeldt-Jakob disease (CJD), an incurable and ultimately fatal neurodegenerative disorder, according to a study by National Institutes of Health (NIH) scientists ...
Aug 6, 2014
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0
Neuroscience
Discovery illuminates how brain cells die in prion diseases
Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form within and kill brain cells ...
Dec 22, 2021
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254
Genetics
Genetic study finds epidemic of kuru likely led to migration of women in the Eastern Highlands of Papua New Guinea
In the most comprehensive genetic study of the people living in the Eastern Highlands of Papua New Guinea to date, researchers from Papua New Guinea and the U.K. reveal the complex population structure and migration patterns ...
Mar 19, 2024
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14
Neuroscience
Scientists identify locations of early prion protein deposition in retina
The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes ...
Jan 29, 2021
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2
Neuroscience
New MRI technique may predict progress of dementias
A new technique for analyzing brain images offers the possibility of using magnetic resonance imaging (MRI) to predict the rate of progression and physical path of many degenerative brain diseases, report scientists at the ...
Apr 10, 2012
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0
Neuroscience
CSF RT-QuIC has high diagnostic specificity, sensitivity for prions
(HealthDay)—Cerebrospinal fluid (CSF) real-time quaking-induced conversion (RT-QuIC) has high diagnostic specificity and sensitivity for prion diseases, according to a study published online Nov. 28 in the Annals of Neurology.
Dec 3, 2016
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2
Diseases, Conditions, Syndromes
Viral infections could promote neurodegeneration
Some viral diseases could possibly contribute to neurodegeneration. DZNE researchers report this in the journal Nature Communications. Their assessment is based on laboratory experiments in which they were able to show that ...
Oct 19, 2021
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