Genetic and mechanistic basis for rotor syndrome uncovered

The main symptom of Rotor syndrome is jaundice caused by a buildup of a substance known as conjugated bilirubin. Bilirubin is a yellow substance generated in large quantities when the body recycles red blood cells. It is ...

Rotor syndrome, also called Rotor type hyperbilirubinemia, is a rare, relatively benign autosomal recessive bilirubin disorder of unknown origin. It is a distinct disorder, yet similar to Dubin-Johnson syndrome — both diseases cause an increase in conjugated bilirubin.

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