Squamous Cell Carcinoma

Corynebacterium, Kingella abundance tied to HNSCC risk

(HealthDay)—The overall oral microbiome composition is not associated with the risk of head and neck squamous cell carcinoma (HNSCC), but greater abundance of genera Corynebacterium and Kingella is associated with decreased ...

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New method for suppressing lung cancer oncogene

Researchers at Okayama University describe in Oncotarget an approach for suppressing the expression of the SOX2 protein, an oncogene associated with both lung and esophageal cancer. The procedure, based on the targeted delivery ...

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How to do a skin cancer body check

(HealthDay)—Every year, about 5 million Americans are treated for skin cancer—an abnormal growth of skin cells that most often develops on areas exposed to the sun.

Nov 15, 2017
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Squamous cell carcinoma (SCC or SqCC) is a form of skin cancer. Skin cancers fall into two groups, melanoma and non-melanoma; squamous cell carcinoma is a non-melanoma cancer. It is one of the most common cancers in humans and other animals.

Squamous cells are a type of epithelium cell forming the outermost layers of the skin and some organs in the body. Squamous cell carcinoma usually occurs on the skin, especially portions commonly exposed to the Sun, the face, ears, neck, hands, or arm. The main symptom is a growing bump that may have a rough, scaly surface and flat reddish patches. It may also occur inside the body wherever squamous cells are found, including the esophagus, urinary bladder, prostate, lung, vagina, and cervix, among others.

Despite the common name, squamous cell carcinomas arising in different body sites can show tremendous differences in their presenting signs and symptoms, natural history, prognosis, and response to treatment.

Though the use of these terms has been decreasing in the literature, SqCC is still sometimes referred to as "epidermoid carcinoma" and "squamous cell epithelium". During its earliest stages, it is sometimes known as "Bowen's disease".

This text uses material from Wikipedia licensed under CC BY-SA

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