Diabetes

FDA approves two new medications for diabetes

(HealthDay)—Two new diabetes treatments, Tresiba (insulin degludec injection) and Ryzodeg (insulin degludec/insulin aspart injection), have been approved by the U.S. Food and Drug Administration.

Health

Chemical exposure linked to rising diabetes, obesity risk

Emerging evidence ties endocrine-disrupting chemical exposure to two of the biggest public health threats facing society - diabetes and obesity, according to the executive summary of an upcoming Scientific Statement issued ...

Diabetes

Novel mechanism of insulin resistance in type 2 diabetes

Insensitivity to insulin, also called insulin resistance, is associated with type 2 diabetes and affects several cell types and organs in the body. Now, scientists from Sweden's Karolinska Institutet have discovered a mechanism ...

Cardiology

Study: Type 2 diabetes pill Jardiance cuts risk of death

Jardiance sharply reduced chances of dying in diabetic patients at high risk of heart complications, a study shows, making the Type 2 diabetes medication the first shown to lengthen diabetics' lives.

Diabetes

Morbidly obese toddler had adult diabetes: report

A three-year-old who tipped the scales at 35 kilograms (77 pounds) has become one of the youngest people ever diagnosed with a lifestyle-related form of diabetes that strikes adults, her doctor said Thursday.

Medical research

Mitochondrial function changes as we age

(Phys.org)—A new study finds that age-related onset of type 2 diabetes and impaired glucose tolerance may be due to the lowered ability of muscle mitochondria to switch from metabolizing fatty acids to metabolizing glucose ...

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Diabetes mellitus type 2 – formerly non-insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes – is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. The classic symptoms are excess thirst, frequently having to urinate, and constant hunger. Type 2 diabetes makes up about 90% of cases of diabetes with the other 10% due primarily to diabetes mellitus type 1 and gestational diabetes. Obesity is the primary cause of type 2 diabetes in people who are genetically predisposed to the disease.

Type 2 diabetes is initially managed by increasing exercise and dietary modification. If blood sugars are not lowered by these measures, medications such as metformin or insulin may be needed. In those on insulin there is typically the requirement to routinely check blood sugar levels.

Rates of diabetes have increased markedly over the last 50 years in parallel with obesity. As of 2010 there are approximately 285 million people with the disease compared to around 30 million in 1985. Long-term complications from high blood sugar can include heart attacks, strokes, diabetic retinopathy where eye sight is affected, kidney failure which may require dialysis, and poor circulation of limbs leading to amputations. The acute complication ketoacidosis is uncommon unlike in type 1 diabetes, nonketonic hyperglycemia however may occur.

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