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Endocrinology & Metabolism news

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Genetics

The gut microbiome can influence hormone levels, mouse study shows

Researchers at the Francis Crick Institute have shown that the balance of bacteria in the gut can influence symptoms of hypopituitarism in mice. They also showed that aspirin was able to improve hormone deficiency symptoms ...

Endocrinology & Metabolism

How male hormones regulate skeletal muscle function

Male hormones (androgens), as their name implies, have an important role in promoting the formation of male sexual characteristics (secondary sexual characteristics). In addition, androgens have anabolic effects, as indicated ...

Diabetes

Novel regulator of glucose transport in adipose tissue discovered

The role of the adapter protein PICALM (phosphatidylinositol-binding clathrin assembly protein) in the development of Alzheimer's disease is well documented. Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke ...

Endocrinology & Metabolism

Study looks at impact of peritoneal dialysis on thyroid function

Patients undergoing peritoneal dialysis (PD) have significantly higher thyroxine (T4) concentrations than hemodialysis (HD) patients and higher free T4 (FT4) concentrations at 12 and 24 months, according to a study published ...

Overweight & Obesity

Guidance provided for management of obesity in kidney disease

In a report issued by the American Society of Nephrology and published online Sept. 18 in the Journal of the American Society of Nephrology, guidance is presented for the management of obesity in persons with kidney disease.

Medications

Weight loss drugs could help fight fatty liver disease

In the fight against fatty liver disease, researchers are looking for any and all possible solutions. But to combat the disease, which is also known as metabolic dysfunction-associated steatotic liver disease, or MASLD, scientists ...

Overweight & Obesity

New cells could be key to treating obesity

Understanding how fat tissue forms and functions is crucial for addressing obesity and related metabolic diseases. However, adipose tissue, or body fat, behaves differently based on its location in the body.

Sleep disorders

Could getting enough sleep help prevent osteoporosis?

As part of the University of Colorado Department of Medicine's annual Research Day on April 23, faculty member Christine Swanson, MD, MCR, described her clinical research on whether adequate sleep can help prevent osteoporosis.

Oncology & Cancer

How cancer cells harness energy to drive disease progression

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that ...

Cardiology

Dietary changes may help treat pulmonary hypertension

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart ...

Overweight & Obesity

BRD7 research points to alternative insulin signaling pathway

Bromodomain-containing protein 7 (BRD7) was initially identified as a tumor suppressor, but further research has shown it has a broader role in other cellular processes, including the remodeling of chromosomes and cell cycle ...

Overweight & Obesity

New regulator of eating behavior identified

The rapidly escalating prevalence of overweight and obesity poses a significant medical challenge worldwide. In addition to people's changing lifestyles, genetic factors also play a key role in the development of obesity.

Overweight & Obesity

New drug candidate reverses obesity in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block ...