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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Inflammatory disorders

Wearable sweat sensor detects molecular hallmark of inflammation

The vast majority of diseases and disorders afflicting humans, ranging from arthritis to Zika fever, involve some level of inflammation. While inflammation is most familiar to us as pain, redness, and swelling, a slew of ...

Neuroscience

How inflammation affects brain development

It has long been recognized that too much inflammation in the womb can harm an unborn baby's brain development, but exactly how it happens has been a mystery until now.

Diseases, Conditions, Syndromes

Eosinophilic cellulitis seems to be type 2 inflammatory disease

Eosinophilic cellulitis seems to be a type 2 inflammatory disease, with preferential activation of the Janus kinase (JAK)1/JAK2-signal transducer and activator of transcription (STAT)5 pathways, according to research published ...

Immunology

Researchers uncover a cellular process that leads to inflammation

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses. Their findings, published in the journal Science Immunology, open ...

Immunology

New study gives clues on why exercise helps with inflammation

Researchers have long known that moderate exercise has a beneficial impact on the body's response to inflammation, but what's been less understood is why. New research coming out of York University done on a mouse model suggests ...

Inflammatory disorders

Q and A: Childhood eczema

DEAR MAYO CLINIC: My 2-year-old son has a new rash on his arms and back. His doctor said it looks like eczema. He is itching nonstop and that creates red, raw skin. It seems to be worse while he's lying in bed. No one in ...

Immunology

Novel approach could redefine allergy treatment

For years, research and therapies for allergic asthma have been focused largely on targeting the inflammatory cytokines in the body that react to allergens and cause overproduction of mucus, wheezing and difficulty breathing. ...

Immunology

Researchers uncover immune system signaling complex

A study led by Daniel Jane-Wit, MD, Ph.D., a Yale School of Medicine associate professor of medicine (cardiology) and of immunobiology, could revolutionize our understanding of immune signaling. The study, published May 24 ...