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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Inflammatory disorders

Self-help aids quality of life for people with psoriasis

(HealthDay)—Self-help based on compassion and mindfulness is acceptable to users and can reduce feelings of shame and improve quality of life for people living with psoriasis, according to a study published online Jan. ...

Inflammatory disorders

Inflammatory bowel disease: Incidence and treatment

Inflammatory bowel disease (IBD), with its two main disease entities Crohn's disease and ulcerative colitis, is a chronic and relapsing inflammation of the gastrointestinal tract. The highest prevalence of IBD is found in ...

Diseases, Conditions, Syndromes

FDA approves Rinvoq for treatment of atopic dermatitis

The U.S. Food and Drug Administration approved Rinvoq (upadacitinib) for the treatment of moderate-to-severe atopic dermatitis in patients aged 12 years and older, the manufacturer announced Friday.

Diseases, Conditions, Syndromes

Ion channel regulates molecule that contributes to COPD

Chronic obstructive pulmonary disease—COPD for short—is one of the most common diseases of the lung. It affects almost 300 million people worldwide, of which about three million die every year. A collective term for chronic ...

Genetics

Uncovering cellular mechanisms of genetic skin diseases

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

Inflammatory disorders

Can severe weather changes make allergies worse?

Although allergies are normally associated with the spring and fall, it may feel like allergy season never left this winter. From cold fronts to rainy days and back to warmer days, an allergy expert at Baylor College of Medicine ...

Inflammatory disorders

AI improves accuracy of antibiotic selection for UTI treatment

Doctors at Maccabi Healthcare Services have recently begun to work with an AI-based predictive algorithm developed by the Technion–Israel Institute of Technology together with KSM (Kahn-Sagol-Maccabi), the Maccabi Research ...

Medical research

Tracking the spread of tuberculosis in Brazilian prisons

COVID-19 has nothing on tuberculosis. The bacterial infection has ravaged humanity for thousands of years—accounting for one quarter of all deaths in the United States and Europe for 300 years before the discovery of antibiotics.

Inflammatory disorders

'Freedom from disease' in psoriasis is multicomponent concept

(HealthDay)—For people with psoriasis, "freedom from disease" is a multicomponent concept that includes five main domains, according to research published online Nov. 24 in the Journal of the European Academy of Dermatology ...

Inflammatory disorders

AI allows automated scoring of psoriasis area, severity

(HealthDay)—Deep learning algorithms, such as convolutional neural networks (CNNs), can automatically and objectively perform image-based Psoriasis Area and Severity Index (PASI) scoring, according to a study published ...

Health

Stress less – it might protect you from COVID

While stress has always been around, in 2021, it has seemed utterly inescapable. Between the stress of family possibly getting very ill, increased care responsibilities, perpetual concern about lost income, the pain of social ...