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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Medical research

Breakthrough technique for treating inflammatory disease

Ground-breaking research from Heriot-Watt University and the University of Texas Medical Branch is set to be commercialized following a funding award from Scottish Enterprise's High Growth Spinout Programme.

Neuroscience

Exploring psychosomatic inflammation

Your phone pings. It's a notification from your friend, who you just went out for a drink with last night. According to her text, she has just tested positive for COVID-19. You start feeling your throat, you sneak a short ...

Diabetes

Galectin-1 linked to increased risk of type 2 diabetes

Researchers at the University of Gothenburg now associate elevated levels of the protein galectin-1 with increased risk of developing type 2 diabetes about 18 years later. At the same time, this protein seems to be a protective ...

Medical research

Flicking the inflammation off-switch

In a long-term collaboration between researchers and industry, an exciting first step has been made in the creation of a new generation of medicines for auto-immune diseases using one of our body's own anti-inflammatory off-switch ...

Medical research

Scientists discover a target to treat fatty liver disease

About 80 million Americans have fatty liver disease unrelated to alcohol abuse. Nonalcoholic fatty liver disease is associated with obesity and diabetes, and can lead to more severe liver damage such as nonalcoholic steatohepatitis ...

Medical research

Fermented soybeans suppress asthma-induced airway inflammation

Bronchial asthma causes symptoms such as wheezing and cough due to chronic airway inflammation, but there is no fundamental treatment for it, leaving a desire for new prevention and treatment methods. Now a new study reveals ...

Diseases, Conditions, Syndromes

Predictors explored for response to UVB phototherapy in psoriasis

The Psoriasis Area and Severity Index (PASI) clearance trajectory over the first few weeks of type B ultraviolet (UVB) phototherapy may predict psoriasis clearance, according to a study published in the November issue of ...

Immunology

Mechanism behind ineffective psoriasis drugs identified

Psoriasis is a chronic inflammatory autoimmune disease that manifests as red, scaly skin patches. There is no causal treatment for the disease, but the symptoms can be significantly alleviated with modern therapies. Complex ...

Arthritis & Rheumatism

Discovery of a potential new therapy for inflammatory arthritis

In a paper published today in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute, part of University Health Network (UHN) in Toronto, have made a discovery that could lead to new ...

Medications

Nutrients can mimic pharmacological effects of medicines

Nutrients can work in surprisingly similar ways as medicines. Pharmacologists from Utrecht University conclude that more knowledge of the similarities between food and medicines could help develop diets to combat diseases.