Protein shapes matter in Alzheimer's research
Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.
May 12, 2020
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Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.
May 12, 2020
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125
When tested in brain cells and in a mouse model of Alzheimer's disease, a new compound significantly reduced the number of amyloid plaques in the brain, lessened brain inflammation and diminished other molecular markers of ...
May 7, 2020
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Alzheimer's disease is the leading cause of dementia in the U.S., with approximately 5.4 million currently affected and an estimated 16 million by 2050. Damage to the brain from Alzheimer's disease occurs years before patients ...
Nov 12, 2019
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The growing popularity of microdosing—taking tiny amounts of psychedelic drugs to boost mood and mental acuity—is based on anecdotal reports of its benefits. Now, a study in rats by researchers at the University of ...
Mar 4, 2019
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A team of scientists led by chemists Stephen Martin and James Sahn at The University of Texas at Austin have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway. The synthetic ...
Aug 16, 2017
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A team of researchers from the University of Saskatchewan has developed two caffeine-based chemical compounds that show promise in preventing the ravages of Parkinson's disease.
Sep 30, 2016
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For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous ...
Jan 17, 2012
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Drugs called interferon betas are common treatments for multiple sclerosis (MS), reducing relapses and slowing motor function decline. Interferon beta, a protein known to contain a zinc binding pocket, is thought to reduce ...
Aug 10, 2022
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Many brain diseases and disorders lead to neuroinflammation, a swelling of brain tissue that is increasingly recognized as one ofthe telltale signs and disease progression factors of Alzheimer's and Parkinson's disease. Neuroinflammation ...
Mar 31, 2022
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Our body is tuned to function in a synchronous manner with a "circadian" or day-and-night rhythm. Alterations to daily lifestyles due to the current stressful routines people follow can disrupt the body's day-night cycle ...
Aug 19, 2021
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