Aging Cell

Medical research

Ageing impairs critical final egg maturation stage

Age may adversely affect women's fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological pathways during the final maturation stage of a human egg cell, according ...

Genetics

New, highly precise 'clock' can measure biological age

Using the model organism Caenorhabditis elegans, researchers at the University of Cologne have developed an 'aging clock' that reads the biological age of an organism directly from its gene expression, the transcriptome. ...

Medical research

Single-cell technique could provide 'egg health' indicators

Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to ...

Medical research

Senescent cells may be good when it comes to a bad injury

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases. Now scientists have some of the first evidence that at a younger age at least, ...

Oncology & Cancer

NSD2 enzyme appears to prevent cellular senescence

Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging. Their experiments ...

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