Antimicrobial Agents and Chemotherapy

Diseases, Conditions, Syndromes

Resistance to last resort drug arose in patient over 3 weeks

French investigators have described development of resistance to one of the last resort therapies used to treat extremely drug-resistant Pseudomonas aeruginosa. That resistance arose in a single patient over a scant 22 days. ...

Medications

New study is 'chilling commentary' on future of antibiotics

The health care market is failing to support new antibiotics used to treat some of the world's most dangerous, drug-resistant "superbugs," according to a new analysis by University of Pittsburgh School of Medicine infectious ...

Medications

In search of clues to fight antibiotic resistance

To combat the rise of drug-resistant bacteria, researchers are examining how one superbug adapts to fight an antibiotic of last resort, hoping to find clues that can prolong the drug's effectiveness.

Diseases, Conditions, Syndromes

New gene variant is even more resistant to hospital antiseptic

A team of investigators has discovered a new, more powerful variant on an antimicrobial resistance gene common among Staphylococcus species. The gene protects the bacteria from an antiseptic compound widely used in healthcare. ...

Medications

Antibiotic resistance across Wisconsin revealed by new maps

When a patient arrives at a hospital with an infection, her doctor must decide which antibiotic might have the best chance of curing her—no easy feat when disease-causing pathogens are increasingly resistant to multiple ...

Genetics

A quick path to antimalarial resistance

Resistance to antimalarial drugs is thought to result mainly from changes in the parasite's genome. However, P. falciparum can also develop resistance to some antimalarial compounds by epigenetic changes, according to a new ...

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