Biophysical Journal

Oncology & Cancer

Learning how cancer cells collaborate to multiply and metastasize

Cancer cells are known to migrate and collaborate to form networks that function as conduits providing access to nutrients and blood vessels. Now, researchers in Japan have generated similar large-scale structures from cancer ...

Medical research

A better understanding of the von Willebrand Factor's A2 domain

Under normal, healthy circulatory conditions, the von Willebrand Factor (vWF) keeps to itself. The large and mysterious multimeric glycoprotein moves through the blood, balled up tightly, its reaction sites unexposed. But ...

Oncology & Cancer

'Idling' cancer cells may return

About half of all melanomas have mutations in the BRAF gene that accelerate tumor cell growth and spread. While most patients benefit from targeted anti-BRAF therapy, resistance to treatment and tumor progression is almost ...

Medical research

A minimally invasive tool to measure muscle impairment

A minimally invasive, fiber-optic technique that accurately measures the passive stretch and twitch contraction of living muscle tissue could someday be an alternative to the painful muscle biopsies used to diagnose and treat ...

Medical research

Muscles more sensitive to stretch than previously thought

Almost 50 years after Nobel prize-winner Andrew Huxley published his seminal findings about muscle contraction, scientists from the University of Bristol have retraced Huxley's steps. Their findings, published today in the ...

Medical research

Cell softness predicts corneal transplant success

Stem cell transplantation is a promising strategy for restoring eyesight resulting from corneal damage, but tissue grafts must contain a high percentage of stem cells for clinical success. A study published October 18 in ...

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