For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments. The compound, called ONC201, nearly ...
Aug 16, 2023
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The transfer of a neurotransmitter from one type of skin cell to another (melanocytes to keratinocytes) altered electrical activity and promoted melanoma initiation in preclinical models, according to results published in ...
Aug 9, 2023
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A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS), led by Assistant Professor Anand Jeyasekharan, has discovered a unique combination of oncogenes ...
Jul 19, 2023
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Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a rare hereditary syndrome ...
Jul 13, 2023
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Applying the same solution to different problems is a common mistake, not only among humans but also in our immune system. Flooding a wound with inflammation-causing white blood cells can be helpful for fighting infection, ...
May 8, 2023
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The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ...
May 4, 2023
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Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. It's also one of the deadliest. More than 90% of PDAC patients die within five years of diagnosis. Usually, by the time the cancer is identified, ...
Apr 26, 2023
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Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.
Apr 24, 2023
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Researchers from the National Institutes of Health (NIH) have outlined opportunities for achieving President Biden and First Lady Biden's Cancer Moonshot national goal of reducing the cancer death rate by at least 50% over ...
Apr 17, 2023
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A new study led by researchers at The University of Texas MD Anderson Cancer Center has discovered that co-occurring mutations in three tumor suppressor genes—KEAP1, SMARCA4 and CDKN2A—are linked with poor clinical outcomes ...
Apr 17, 2023
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