Cell Cycle is a peer-reviewed scientific journal covering cell biology. The editor-in-chief is Mikhail V. Blagosklonny (Roswell Park Cancer Institute). Cell Cycle is abstracted and indexed in Medline/PubMed and the Science Citation Index Expanded.
Mutations of the alkaline phosphatase (ALPL) gene in the liver, bone and kidney can cause hypophosphatasia (HPP) and early-onset bone dysplasia, asserting its key role in human bone development. Despite its importance, its ...
Institute researchers have uncovered new insights into how the normal controls on cell growth are lost in cancer cells, leading to rapid tumour expansion.
Oct 29, 2018
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(Medical Xpress)—Every day, some of your cells stop dividing, and that's a good thing. Cells that proliferate indefinitely are immortal, an essential early step in the development of most malignant tumors.
Nov 7, 2014
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Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer ...
Jan 7, 2013
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Autophagy is a process by which cells clean themselves of damaged organelles, and for self-execution. This adaptive mechanism supports a healthy phenotype on the cellular level. Autophagy is activated in certain cases of ...
Aug 13, 2018
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Insilico Medicine, Inc in collaboration with scientists from Atlas Regeneration, Inc, Vision Genomics, Inc and Howard University published two research papers on fibrosis in the lung and liver and fibrotic signatures in glaucoma. ...
Jul 29, 2016
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Working with human breast cancer cells, a team of scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have successfully turned off a misbehaving protein that fuels the growth of a particularly aggressive, ...
Apr 4, 2016
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Senescence, a phenomenon in which cells cease to divide and grow, can be caused by everything from natural DNA damage to treatment with chemotherapy. However, several mechanisms allow for cells to bypass senescence and grow ...
Jun 2, 2015
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Leukemia cells from chronic myeloid leukemia patients, especially those in the advanced stage, lack the BRCA1 protein. Importantly, the protein is not present even if the patient carries the proper, unmutated gene responsible ...
Mar 26, 2015
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Virginia Tech biochemists are trying to deliver a stern wake-up call to the parasite that causes sleeping sickness.
Feb 24, 2015
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