Cell Chemical Biology (previously, Chemistry & Biology) publishes reports of novel investigations in all areas at the interface of chemistry and biology. Chemistry & Biology strongly encourages submission of articles in which chemical tools are used to provide unique insight into biological function and mechanism. Studies that illustrate the underlying chemistry of biological processes will also be viewed favorably. Other relevant studies of interest to chemists and biologists will also be considered. In general, to be considered suitable for publication in this journal, investigations that primarily have a genetic, computational, or theoretical focus must contain substantiating experimental data. All articles should not only be of significance to the immediate field but should also be of interest to our diverse readership from the broad chemical-biology community.
New insights into the pathogenesis of Alzheimer's disease could unlock novel therapeutic approaches and help to prevent the disease. A study led by Professors Marcus Grimm and Tobias Hartmann at the Rhineland Campus of the ...
Nov 28, 2023
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Cancer drugs often don't behave as expected in clinical trials. A study published Oct. 11 in the journal Cell Chemical Biology explores why drugs under development are unlikely to work due to insufficient genetic analysis.
Oct 25, 2023
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Targeted cancer drugs are widely used because of their ability to inhibit specific proteins involved in cancer development with fewer side effects compared to chemotherapy drugs. But targeted therapies can often inhibit other ...
Oct 16, 2023
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Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, have published a new study explaining how they took a protein once thought to be too challenging for targeted ...
Aug 1, 2023
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Chronic wounds are open sores or injured tissue that fail to heal properly. These types of wounds are notoriously challenging to treat because of bacterial infections like Staphylococcus aureus, or S. aureus. Additionally, ...
May 22, 2023
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Since the 1930s, scientists have explored a virus called LCMV (short for lymphocytic choriomeningitis virus) to reveal the hidden workings of the immune system. The virus is carried by rodents, which makes it a useful tool ...
Mar 28, 2023
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Researchers at the Indian Institute of Science (IISc) and their collaborators have identified a key role played by hydrogen sulfide (H2S) gas in suppressing the human immunodeficiency virus (HIV). Increased H2S was found ...
Dec 7, 2021
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Activating the immune system at the site of a tumor can recruit and stimulate immune cells to destroy tumor cells. One strategy involves injecting immune-stimulating molecules directly into the tumor, but this method can ...
Nov 12, 2021
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In a long-term collaboration between researchers and industry, an exciting first step has been made in the creation of a new generation of medicines for auto-immune diseases using one of our body's own anti-inflammatory off-switch ...
Nov 5, 2021
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MIT chemical engineers have developed a way of swiftly screening compounds to determine their therapeutic potential for certain kinds of cancers. With a genetically engineered sensor and high-throughput technology, their ...
Nov 4, 2021
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