Injured hearts do not heal themselves. Heart muscle cells, or cardiomyocytes, do not proliferate as much as necessary to replace dead tissue with new, pumping cells. Consequently, most people who had a severe heart attack ...
Feb 14, 2019
3
70
Nearly two decades after a class of once-promising cancer drugs called MMP inhibitors mysteriously failed in clinical trials, scientists think they may have an explanation for what went wrong.
Jan 24, 2019
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25
Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth. Tumor necrosis factor-α (TNFα) coordinates cell death in a variety ...
Jan 17, 2019
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1
Like detectives tracking a serial killer, St. Jude Children's Research Hospital scientists have identified a novel mechanism that may help promote the growth and spread of solid tumors. The findings appeared online Oct. 25 ...
Oct 31, 2018
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22
Chronic excessive caloric intake leads to the deposition of fat droplets in the liver. This condition, known as fatty liver, can cause permanent damage to the organ. Researchers at the Max Planck Institute of Biochemistry ...
Oct 26, 2018
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144
A team of researchers led by Principal Investigator Dr. Jan Gruber from Yale-NUS College has discovered a combination of pharmaceutical drugs that not only increases healthy lifespan in the microscopic worm Caenorhabditis ...
Oct 22, 2018
1
1804
Metastatic tumours are characterised by a high degree of chromosomal instability—that is to say a constant change in the number and structure of chromosomes they hold. In spite of this observation, it is unknown whether ...
Sep 26, 2018
0
0
University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development ...
Sep 14, 2018
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56
The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...
Aug 24, 2018
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104
Dogs, known for their extraordinarily keen senses of smell, can be trained to use their sensitive sniffers to find drugs, bombs, bed bugs, missing hikers and even cancer. Among dogs and other animals that rely on smell, at ...
Aug 10, 2018
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