Genetics
Study offers clues to cause of kids' brain tumors
(Medical Xpress)—Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.
Nov 16, 2012
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Genes & Development
Genetics
Researchers describe mechanism behind progeria
Progeria, a premature aging disease, is the research focus of Roland Foisner's team at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna. Children suffering from progeria die ...
Oct 6, 2015
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Genetics
Cellular factors that shape the 3-D landscape of the genome identified
Researchers, using novel large-scale imaging technology, have mapped the spatial location of individual genes in the nucleus of human cells and identified 50 cellular factors required for the proper three-dimensional (3D) ...
Aug 14, 2015
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Medical research
Brain glia cells increase their DNA content to preserve vital blood-brain barrier
The blood-brain barrier is essential for maintaining the brain's stable environment—preventing entry of harmful viruses and bacteria and isolating the brain's specific hormonal and neurotransmitter activity from that ...
Jan 13, 2012
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Genetics
Long non-coding RNA prevents the death of maturing red blood cells
A long non-coding RNA (lncRNA) regulates programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. This is the first time a lncRNA has been found ...
Dec 7, 2011
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Immunology
Diabetes drugs act as powerful curb for immune cells in controlling inflammation
When tissue is damaged, one of the body's first inflammatory immune-system responders are macrophages, cells which are commonly thought of as "construction workers" that clear away damaged tissue debris and initiate repair. ...
Jul 27, 2018
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Oncology & Cancer
Researcher finds keys to control the 'driver of cancer's aggressiveness'
'Do not erase.' 'Recycle me.' 'Free to a good home.' Humans post these signs to indicate whether something has value or not, whether it should be disposed of or not. Inside our cells, a sophisticated recycling system uses ...
Sep 17, 2020
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176
Genetics
Tumor-suppressing gene restrains mobile elements that can lead to genomic instability
The most commonly mutated gene in cancer, p53, works to prevent tumor formation by keeping mobile elements in check that otherwise lead to genomic instability, UT Southwestern Medical Center researchers have found.
Jan 22, 2016
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114
Genetics
Study identifies key regulator of cell differentiation
Embryonic stem cells and other pluripotent cells divide rapidly and have the capacity to become nearly any cell type in the body. Scientists have long sought to understand the signals that prompt stem cells to switch off ...
Feb 21, 2022
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425
Genetics
From plants, team extracts a better way to determine what our genes do
Scientists at the University of Virginia School of Medicine have developed a better way to determine what our genes do, allowing scientists to better probe the genetic causes of diseases and more efficiently determine whether ...
Nov 8, 2019
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