Genome Research

Publisher
Cold Spring Harbor Laboratory Press
Country
United States
History
1991-present
Impact factor
13.588 (2010)

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Genetics

Are mosaic embryos the 'dark horse' of IVF?

Not every embryo contains 46 perfect chromosomes. Some have more, others have fewer. The result is a common abnormality known as aneuploidy, which occurs in as many as 80 percent of human embryos.

Genetics

Cancer-preventing protein finds its own way in our DNA

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair ...

Oncology & Cancer

Massive genome havoc in breast cancer is revealed

In cancer cells, genetic errors wreak havoc. Misspelled genes, as well as structural variations—larger-scale rearrangements of DNA that can encompass large chunks of chromosomes—disturb carefully balanced mechanisms that ...

Genetics

Uncovering a 'smoking gun' of biological aging clocks

A newly discovered ribosomal DNA (rDNA) clock can be used to accurately determine an individual's chronological and biological age, according to research led by Harvard T.H. Chan School of Public Health. The ribosomal clock ...

Oncology & Cancer

Ancient viruses could help kill cancers

DNA "echoes" of viruses that infected our ancestors millions of years ago could help the immune system to identify and kill cancer cells, according to new research from Crick scientists.

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