iScience

Science has many big remaining questions. To address them, we will need to work collaboratively and across disciplines. The goal of iScience is to help fuel that type of interdisciplinary thinking. iScience is a new open-access journal from Cell Press that provides a platform for original research in the life, physical, and earth sciences. The primary criterion for publication in iScience is a significant contribution to a relevant field combined with robust results and underlying methodology. The advances appearing in iScience include both fundamental and applied investigations across this interdisciplinary range of topic areas. To support transparency in scientific investigation, we are happy to consider replication studies and papers that describe negative results.

Publisher
Cell Press
Website
https://www.cell.com/iscience/home

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Endocrinology & Metabolism

Acetylation: A timekeeper of glucocorticoid sensitivity

Cortisol, also commonly known as the stress hormone, belongs to the family of glucocorticoids. In addition to its physiological function, synthetic derivatives of cortisol are also used as anti-inflammatory drugs. In the ...

Overweight & Obesity

Obesity disrupts normal liver function in mice, study finds

Your liver plays a vital role in your metabolism, the biological process that converts food into energy. We know that being overweight can negatively affect metabolic activity, but not exactly how. To better understand this, ...

Cardiology

New 4D imaging may detect poor pumping in deadly heart disease

In a new study published in iScience, Mayo Clinic researchers found that a novel 4D echo imaging method that measures cardiac strain may detect subtle changes in the heart's dysfunction during acute myocarditis, a deadly ...

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