Journal of Alzheimer's Disease

Alzheimer's disease & dementia

Damage early in Alzheimer's disease identified via novel MRI approach

Alzheimer's disease usually is diagnosed based on symptoms, such as when a person shows signs of memory loss and difficulty thinking. Up until now, MRI brain scans haven't proven useful for early diagnosis in clinical practice. ...

Alzheimer's disease & dementia

APOE E2/E2 genotype offers some protection from cognitive decline

The APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins that builds up in the brain in Alzheimer's disease—exists in three allelic forms: E4, ...

Alzheimer's disease & dementia

Happiness in early adulthood may protect against dementia

While research has shown that poor cardiovascular health can damage blood flow to the brain increasing the risk for dementia, a new study led by UC San Francisco indicates that poor mental health may also take its toll on ...

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