Journal of Biological Chemistry

Medical research

Researcher finds surprising results in high-altitude study

From battling stomach bugs to figuring out where to find deionized water, carrying out a scientific expedition in the Andes is no small feat. "We ended up using pressure cookers to sterilize our research equipment," said ...

Immunology

Gene discovery unlocks mysteries to our immunity

Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.

Oncology & Cancer

The sugar-attaching enzyme that defines colon cancer

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry. The enzyme appears to drive ...

Oncology & Cancer

Researchers report a new target to treat prostate cancer

The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer. EGFR, present on the cell membrane, ...

Genetics

Study sheds light on rarity of disease-causing IGF mutations

Peter Rotwein, M.D., was recently spotlighted by the American Society for Biochemistry and Molecular Biology (ASBMB) for a study he conducted on insulin-like growth factors (IGFs), a family of proteins that are crucial in ...

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