Journal of Cell Biology

Medical research

Mobilizing mitochondria may be key to regenerating damaged neurons

Researchers at the National Institute of Neurological Disorders and Stroke have discovered that boosting the transport of mitochondria along neuronal axons enhances the ability of mouse nerve cells to repair themselves after ...

Medical research

Mouse study links heart regeneration to telomere length

Researchers at the Spanish National Center for Cardiovascular Research have discovered that the ends of heart muscle cell chromosomes rapidly erode after birth, limiting the cells' ability to proliferate and replace damaged ...

Oncology & Cancer

How a metabolic pathway promotes breast cancer metastasis

A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal of Cell Biology. The ...

Medical research

Decrypting a collagen's role in schizophrenia

A small peptide generated from a collagen protein may protect the brain from schizophrenia by promoting the formation of neuronal synapses, according to a paper published in The Journal of Cell Biology. The study, "Collagen-Derived ...

Medical research

ROBO1 helps cells put up stiff resistance

A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, "Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK ...

Medical research

Putting the brakes on accelerated aging

Telomeres are to chromosomes what aglets are to shoelaces—protective caps that stop the tightly wound strings from unraveling. Every time a cell divides, its telomeres are trimmed, eventually becoming so short that the ...

Medical research

Biologists identify mechanisms of embryonic wound repair

It's like something out of a science-fiction movie - time-lapse photography showing how wounds in embryos of fruit flies heal themselves. The images are not only real; they shed light on ways to improve wound recovery in ...

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