Journal of Cell Biology

Medical research

Elusive receptor for progranulin found

Progranulin is produced and secreted by most cells in the body. From skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function. In cancer, too much progranulin ...

Immunology

New regulator of immune reaction discovered

Cells of the immune system can distinguish between protein molecules that are "self" and "non-self". For example, if we are exposed to pathogens such as bacteria or viruses that carry foreign molecules on their surface, the ...

Immunology

New target identified to combat deadly allergic reactions

Researchers in France have identified a molecular motor that controls the release of inflammatory factors that cause severe and fatal allergic reactions. The study, "Kinesin-1 controls mast cell degranulation and anaphylaxis ...

Oncology & Cancer

Scientists aim to slow fast growth of cancer cells

The fight against cancer is a marathon, fought step by step, inch by inch. While breakthroughs may be rare, a new study from the Faculty of Medicine & Dentistry is giving greater insight into the growth of cancer cells and ...

Medical research

Tongue-on-a-chip provides insight into genetic diseases

Muscular dystrophy is a group of rare genetic diseases that cause progressive muscle weakness and deterioration. For decades, researchers have struggled to understand how the disease works and to find suitable treatments.

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