Journal of Cell Biology

Cardiology

Two new studies explore the science of cardiovascular diseases

Professor of cardiology Martin A. Schwartz led two recently published studies that advance knowledge of the underlying biology of cardiovascular diseases, which are among the most common causes of chronic illness and death ...

Parkinson's & Movement disorders

Unravelling the biology of parkinsonism

Scientists have taken another step towards understanding the causes of parkinsonism by identifying what's happening at a cellular level to potentially help develop future treatments.

Medical research

Mobilizing mitochondria may be key to regenerating damaged neurons

Researchers at the National Institute of Neurological Disorders and Stroke have discovered that boosting the transport of mitochondria along neuronal axons enhances the ability of mouse nerve cells to repair themselves after ...

Oncology & Cancer

How a metabolic pathway promotes breast cancer metastasis

A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal of Cell Biology. The ...

Medical research

Decrypting a collagen's role in schizophrenia

A small peptide generated from a collagen protein may protect the brain from schizophrenia by promoting the formation of neuronal synapses, according to a paper published in The Journal of Cell Biology. The study, "Collagen-Derived ...

Medical research

ROBO1 helps cells put up stiff resistance

A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, "Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK ...

Medical research

Putting the brakes on accelerated aging

Telomeres are to chromosomes what aglets are to shoelaces—protective caps that stop the tightly wound strings from unraveling. Every time a cell divides, its telomeres are trimmed, eventually becoming so short that the ...

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