Journal of Clinical Investigation is a journal published by the American Society for Clinical Investigation.
New RNA-targeted therapy can halt the progression of a specific type of childhood dementia in mice and holds potential to reverse some of the detrimental effects of this rare disease.
Apr 18, 2024
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Through millions of years of evolutionary refinement, the human body has developed a sophisticated surveillance mechanism—the immune system. This intricate network is constantly scanning the body for invaders such as bacteria, ...
Apr 17, 2024
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The most common type of lung fibrosis—scarring of the lungs—is idiopathic, meaning of unknown cause. Researchers are urgently trying to find ways to prevent or slow idiopathic pulmonary fibrosis (IPF) and related lung ...
Apr 12, 2024
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Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems—prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, ...
Apr 9, 2024
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A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...
Apr 9, 2024
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Cancer is a prevalent disorder where cells divide and grow uncontrollably and eventually spread to other regions or organs in the body. Non-small cell lung cancer (NSCLC) is a highly prevalent form of lung cancer. Current ...
Apr 2, 2024
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Only a very small percentage of neurons show changes after an epileptic seizure in mice, but these alterations can be permanent and trigger future seizures that can affect the whole brain and lead to impaired cognition, like ...
Mar 22, 2024
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Scientists have taken a major step towards developing a blood test that could identify millions of people who unknowingly spread tuberculosis.
Mar 22, 2024
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Northwestern Medicine investigators led by Amy Heimberger, MD, Ph.D., the Jean Malnati Miller Professor of Brain Tumor Research and vice chair for Research in the Department of Neurological Surgery, have discovered a new ...
Mar 21, 2024
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Microvillus inclusion disease (MVID) is a rare type of congenital enteropathy in infants that causes devastating diarrhea and an inability to absorb food. Infants can lose liters of fluid a day, become severely dehydrated, ...
Mar 6, 2024
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