Journal of Clinical Investigation

Diabetes

Drug prevents type 1 diabetes in mice, study finds

The buildup of a substance in the pancreas during the pre-symptomatic stage of Type 1 diabetes is essential to the development of the disease, Stanford University School of Medicine researchers have shown.

Medical research

Flow means 'go' for proper lymph system development

The lymphatic system provides a slow flow of fluid from our organs and tissues into the bloodstream. It returns fluid and proteins that leak from blood vessels, provides passage for immune and inflammatory cells from the ...

Medical research

Stem cells provide lasting pain relief in mice

Chronic pain caused by the nerve damage of type 2 diabetes, surgical amputation, chemotherapy and other conditions is especially intractable because it resists painkilling medications.

Medical research

RNA editing technique treats severe form of muscular dystrophy

An RNA editing technique called "exon skipping" has shown preliminary success in treating a rare and severe form of muscular dystrophy that currently has no treatment, based on a new study from Northwestern Medicine and the ...

Diseases, Conditions, Syndromes

Scientists identify a mechanism of epidemic bacterial disease

Through identification of increased toxin production by epidemic forms of group A streptococcus (the "flesh-eating" bacterium), for the first time scientists are able to pinpoint the molecular events that contribute to large ...

Medical research

Gene fuels age-related obesity and diabetes

Practically everyone gets fatter as they get older, but some people can blame their genes for the extra padding. Researchers have shown that two different mutations in a gene called ankyrin-B cause cells to suck up glucose ...

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