Journal of Clinical Investigation

Arthritis & Rheumatism

A two-pronged approach to keep rheumatoid arthritis in check

Rheumatoid arthritis (RA) is an autoimmune, inflammatory disease. Though the precise mechanism of the disease is only partially understood, people with RA produce antibodies that target their own tissues, contributing to ...

Oncology & Cancer

New study shows antioxidants stimulate blood flow in tumors

Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study from Karolinska Institutet published in the Journal of Clinical Investigation shows. The discovery corroborates ...

Diabetes

Study points to alternate therapy for rare form of diabetes

Vanderbilt University Medical Center researchers say an unexpected finding during the cellular analysis of human pancreatic tissue has revealed new information about a rare type of diabetes and underscores the importance ...

Diseases, Conditions, Syndromes

Genetic flaw causes problems for many with hypothyroidism

With an estimated 120 million prescriptions filled each year, the thyroid medicine levothyroxine (marketed as Synthroid ) is one of the most popular prescription medicines in the United States. Most patients who suffer from ...

Psychology & Psychiatry

Study finds potential new treatment for preventing PTSD

Research led by the Centre for Addiction and Mental Health (CAMH) published in the Journal of Clinical Investigation points to a groundbreaking discovery about a new potential treatment and prevention for post-traumatic stress ...

Diabetes

Discovering how diabetes leads to vascular disease

A team of UC Davis Health scientists and physicians has identified a cellular connection between diabetes and one of its major complications—blood vessel narrowing that increases risks of several serious health conditions, ...

Diabetes

Researchers may be close to a cure for type 1 diabetes

Science could be well on its way to a cure for type 1 diabetes, as researchers hone transplant therapies designed to restore patients' ability to produce their own insulin, experts say.

Diseases, Conditions, Syndromes

Gut microbiome composition could make diarrhea less likely

Antibiotics are known to upset the balance of bacteria in the intestinal tract. In some cases, antibiotics can cause the bacterium Clostridium difficile (C. difficile) to overgrow wildly, causing diarrhea and, in severe cases, ...

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