Journal of Clinical Investigation

Oncology & Cancer

Breast cancer's spread routes mapped

Breast cancer spreads to other organs in the body according to certain specific patterns. This has been shown by a team of researchers from Karolinska Institutet and KTH in Sweden and the University of Helsinki in Finland ...

Oncology & Cancer

Treatment doctor tested on himself can put others into remission

Five years ago, David C. Fajgenbaum, MD, MBA, MSc, both a Penn Medicine researcher and patient, tried an experimental treatment on himself based on his laboratory research findings in the hopes of saving his own life. He ...

Neuroscience

Molecule may be key to pain relief in diabetic neuropathy

A new study published in the Journal of Clinical Investigation has identified a key molecule that contributes to painful diabetic neuropathy, an incurable nerve disease that affects about one-quarter of all patients with ...

Sports medicine & Kinesiology

Why exercise gets harder the less you do 

Doing less exercise could deactivate a vital protein in the body, causing further inactivity and making exercise more difficult, new research suggests.

Medical research

Myeloid immune cells in the blood tied to severe COVID-19

Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease. Researchers at Karolinska Institutet in Sweden have now been able to show that patients with severe COVID-19 ...

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