Journal of Experimental Medicine

The Journal of Experimental Medicine is a peer-reviewed academic journal published by the Rockefeller University Press that publishes research papers and commentaries on the physiological, pathological, and molecular mechanisms that encompass the host response to disease. The journal prioritizes studies on intact organisms and has made a commitment to publishing studies on human subjects. Topics covered include immunology, inflammation, infectious disease, hematopoiesisas, cancer, stem cells and vascular biology. The JEM is second highest (based on impact factor) among the journals that publish basic research articles from all fields of biomedicine. Among all biomedical journals (specialized or nonspecialized) JEM stands among the top 10. The JEM was founded in 1896 at the Johns Hopkins School of Medicine by William H. Welch, the school’s founder and also the first president of the Board of Scientific Directors of the Rockefeller Institute (since re-named the Rockefeller University). From its inception, Welch edited the journal by himself—even editing manuscripts while attending baseball games—and he eventually found that it placed too heavy a burden on his time. By March 1902, the

Publisher
Rockefeller University Press
Country
United States
History
1896–present
Impact factor
14.776 (2010)

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Oncology & Cancer

Tumor vs. immune system: A battle to decide the host's fate

The goal of most cancers is to grow and take over the host's body. The immune system has long been in the crosshairs of cancer researchers, as it plays a central role in defending the human body from foreign invasion. In ...

Diseases, Conditions, Syndromes

Editing mosquito's gene wards off malaria and halts reproduction

Scientists have looked for immune system factors that might help mosquitoes ward off pathogens such as malarial parasites and indirectly protect humans from infection. Yale researchers found one by editing a single gene, ...

Genetics

Scientists find molecular key to body making healthy T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation ...

Immunology

Creatine powers T cells' fight against cancer

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according ...

Oncology & Cancer

Drug shows promise as immune therapy for cancer

A therapy developed by Yale researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. The therapy is effective alone or in combination ...

Alzheimer's disease & dementia

Targeting immune cells may be potential therapy for Alzheimer's

Messy tangles of a protein called tau can be found in the brains of people with Alzheimer's disease and some other neurodegenerative diseases. In Alzheimer's, the tangles coalesce just before tissue damage becomes visible ...

Diseases, Conditions, Syndromes

Researchers identify new therapeutic target for pulmonary fibrosis

Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis (IPF) by killing the cells lining the lung's airways. The study, which will be published October ...

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