Journal of Immunology

Immunology

A new regulator of B cell development

Interleukin-33 (IL-33) drives inflammatory responses in allergic and nonallergic disease. Epithelial cells in the lungs, gastrointestinal tract and elsewhere release IL-33, which activates the ST2 receptor on immune cell ...

Oncology & Cancer

Discovery paves way for precision medicine in future

University of Otago scientists have discovered a way to view the immune cell 'landscape' of bowel cancer tumours, paving the way towards more individualised medicine and treatment for many other diseases in future.

Immunology

Researchers design new anti-influenza drugs

Researchers at LSTM and Imperial College London have designed drugs which could help combat any potential new flu pandemic, by targeting the receptors of the cells by which the virus gains entry to the human body.

Oncology & Cancer

Understanding the emergence of leukemia

Acute T-cell lymphoblastic leukemia is a rare type of blood cancer that affects mostly children. This blood cancer appears from the precursor cells that produce T lymphocytes (a type of white blood cells). A new study from ...

Diseases, Conditions, Syndromes

How herpesviruses shape the immune system

Cytomegalovirus is widespread and remains in the body for a lifetime after infection. In healthy individuals, this virus is usually kept in check, but can become dangerous when the immune system is weakened or during pregnancy. ...

Oncology & Cancer

The immune system's supercell—how it matures

Natural killer cells (NK cells), play an important role in the body's defences against cancer and infections. Now, in a joint project, researchers at Lund University in Sweden, the University of Oxford, and Karolinska Institutet ...

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