The Journal of Medicinal Chemistry (usually abbreviated as J. Med. Chem.), is a peer-reviewed scientific journal, published since 1959 by the American Chemical Society. It was originally published as the Journal of Medicinal and Pharmaceutical Chemistry, but changed its name in 1963 to the current title. Profs. Gunda I. Georg of the University of Minnesota and Shaomeng Wang of the University of Michigan are the Editors of the journal. They took over leadership from Prof. Philip S. Portoghese of the University of Minnesota in 2012. Prof. Portoghese had served as Editor in Chief from 1972 - 2011. The Journal of Medicinal Chemistry publishes original research on the correlation of molecular structure to biological activity with a focus on the relationships of chemistry to biological activity.
A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
Mar 8, 2024
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Drug discovery can be a frustrating process of trial and error. Scientists using fragment-based drug discovery link fragments of different molecules together to create a more potent drug but may not know whether a compound ...
Feb 28, 2024
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A UCF College of Medicine researcher is developing a new treatment that could slow or even stop cancer cells from spreading.
Jan 16, 2024
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The most recent statistics put the number of regular cocaine or crack cocaine users in the world at 20 million. Of these, one in four will become addicted or develop use disorders.
Oct 25, 2023
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Researchers from IBB-UAB have developed a second-generation molecule that significantly improves the stabilization and inhibition of the aggregation of proteins involved in Transthyretin Amyloidosis (ATTR), a group of minority ...
Oct 18, 2023
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Researchers have developed an investigative procedure that makes the early stages of drug discovery more efficient. This test can help scientists identify new biologically active compounds that can be used to develop effective ...
Sep 18, 2023
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You've seen the commercial. The one that ominously tells you if you had chickenpox as a child, the virus that causes shingles is already inside you.
Aug 8, 2023
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A multidisciplinary team made up of doctors and scientists from the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) and the Institute for Research in Biomedicine (IRB Barcelona) has led a study, recently ...
Mar 30, 2023
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Building a new precision cancer treatment comes with no shortage of scientific challenges. Now, a group of University of Florida researchers have made a significant discovery in the effort to develop potent, highly targeted ...
Feb 20, 2023
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Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize ...
Jan 30, 2023
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