Journal of Pathology

Alzheimer's disease & dementia

The molecular mechanisms of Alzheimer's

Late-onset sporadic Alzheimer's disease (AD) accounts for about 99 percent of all cases, and is linked to multiple factors and pathogenetic mechanisms. One important contributor is a protein post-translational modification ...

Oncology & Cancer

Telomere length prognostic in hepatocellular carcinoma

(HealthDay)—Telomere attrition occurs in tumor cells from patients with hepatocellular carcinoma (HCC), and shortened telomeres are independent prognosticators for HCC patients, according to a study published online Aug. ...

Oncology & Cancer

Vitamin A may help improve pancreatic cancer chemotherapy

The addition of high doses of a form of vitamin A could help make chemotherapy more successful in treating pancreatic cancer, according to an early study by Queen Mary University of London (QMUL). The promising initial results ...

Oncology & Cancer

Researchers develop antibody to save cancerous bones

Bone Cancer Primary bone cancer called Osteosarcoma (OS) is a rare cancer most often affecting adolescents and children. While most bone cancers have their origin in other body tissues and spread to the bones through metastases, ...

Alzheimer's disease & dementia

Researchers tackle one of the biggest questions in dementia research

Researchers in Southampton are tackling one of the biggest questions in dementia research; why might current approaches in Alzheimer's trials be failing? The new study is published in the Journal of Pathology and funded by ...

Oncology & Cancer

Cancer turns blood vessels over to its cause

Cancer requires a blood supply to deliver the nutrients and oxygen it needs to grow and survive. It had been thought that tumours create the blood supply they need by stimulating the formation of new blood vessels, a process ...

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