Molecular Cell

Psychology & Psychiatry

Scientists discover link between autism and cognitive impairment

Autism can bestow brilliance as well as cognitive difficulty, but how either scenario plays out in the brain is not clear. Now a study by University of Toronto researchers has found that a tiny gene fragment impacts the brain ...

Genetics

How your DNA takes shape makes a big difference in your health

The more we learn about our genome, the more mysteries arise. For example, how can people with the same disease-causing mutation have different disease progression and symptoms? And despite the fact that it's been more than ...

Neuroscience

Finding a cause of neurodevelopmental disorders

Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability, and developmental delays, yet it is unclear why and how this happens. Scientists suspected a ...

Medical research

Study finds direct oxidative stress damage shortens telomeres

The same sources thought to inflict oxidative stress on cells—pollution, diesel exhaust, smoking and obesity—also are associated with shorter telomeres, the protective tips on the ends of the chromosomal shoelace.

Neuroscience

The mechanism behind the pluripotency-differentiation transition

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells decide ...

Medical research

Study reveals factors behind embryonic stem cell state

Embryonic stem cells (ESC) have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body. The embryonic stem cell state is established and maintained by multiple regulatory ...

Neuroscience

Research reveals how the most common ALS mutation dooms cells

St. Jude Children's Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. The research suggests possible new approaches ...

Oncology & Cancer

Balance of two enzymes linked to pancreatic cancer survival

Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration—functions that must be carefully controlled lest cells get out of control and form a tumor. ...

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