Molecular Therapy

Molecular Therapy is the official journal of the American Society for Gene & Cell Therapy. Available in print and online, Molecular Therapy is dedicated to publishing important peer-reviewed research and cutting-edge reviews and promoting the sciences in genetics, medicine and biotechnology.

Publisher
Nature Publishing Group

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HIV & AIDS

Stem cell gene therapy holds promise for eliminating HIV infection

cientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research are one step closer to engineering a tool that could one day arm the body's immune system to fight HIV—and win. The new technique ...

Medical research

Gene therapy gives long-term protection to photoreceptor cells

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common ...

Diseases, Conditions, Syndromes

Synthetic antibody rapidly protects mice and monkeys from Zika

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5th in the journal Molecular Therapy. Injections of synthetic DNA encoding the potent anti-Zika monoclonal ...

Cardiology

Researchers develop promising new stroke therapy

Researchers at The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have developed a novel stroke therapy that, when tested in mice and dogs, has proven superior to the standard ...

Medical research

Gene therapy cassettes improved for muscular dystrophy

Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance. The cassettes, which carry the therapy into muscle cells, contain newer versions of a miniaturized treatment ...

Medical research

Reducing energy efficiency boosts calorie burning in muscle

What started as an evolutionary protection against starvation has become a biological "bad joke" for people who need to lose weight. The human body doesn't distinguish between dieting and possible starvation, so when there ...

Oncology & Cancer

Reprograming T cells to attack solid tumors

An attractive approach to liver cancer treatment is to bolster the body's own immune defenses. Now an international team involving A*STAR researchers has genetically engineered human T cells to endow them with both specificity ...

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