For years, researchers have been trying to target a gene called MYC that is known to drive tumor growth in multiple cancer types when it is mutated or over-expressed, but hitting that target successfully has proven difficult. ...
Jul 1, 2019
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4
By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids - made from human pluripotent stem cells - researchers have taken an important step toward creating a new technology ...
Oct 23, 2017
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1084
A molecule which, for the last 20 years has been believed to be an indicator of good prognosis in tumours has been shown to have a dark side by new research from The Universities of Manchester, Athens and collaborators, recently ...
Jul 7, 2016
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350
Researchers at The Wistar Institute have described a novel role of nicotinamide adenine dinucleotide (NAD+) metabolism in the ability of senescent cells to release tumor-promoting molecules. This study, published online in ...
Feb 19, 2019
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105
The tissue that lines the uterus, known as the endometrium, serves as the location of embryo implantation and the source of the arteries that lead into the placenta to support a fetus during pregnancy. But in humans, when ...
Jul 28, 2022
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521
Cardiovascular disease (CVD) continue to rank as the top killer in the modern world. This deadly disorder often starts with the buildup of lipid deposits or plaques within the blood vessel, silently setting the stage for ...
Nov 2, 2023
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50
The buildup of scar tissue makes recovery from torn rotator cuffs, jumper's knee, and other tendon injuries a painful, challenging process, often leading to secondary tendon ruptures. New research led by Carnegie's Chen-Ming ...
Nov 25, 2019
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2104
An international team led by Weill Cornell Medical College investigators has illuminated the precise molecular steps that enable pancreatic cancer to spread to the liver—the event that makes the most common form of the ...
May 18, 2015
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269
Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, according to a new study from McMaster University.
Oct 16, 2017
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141
Severe injuries to the lung from diseases such as COVID-19 trigger abnormal stem cell repair that alters the architecture of the lung. The aberrant stem cell differentiation in response to injury can prevent the restoration ...
Dec 30, 2021
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317
