Researchers have been chipping away at the genetic causes of congenital heart disease (CHD) for a couple of decades. About 45% of cases of CHD have an identifiable cause, including chromosomal abnormalities, genetic variants ...
Apr 8, 2024
0
12
A study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date.
Apr 4, 2024
0
16
A Canadian-led study has identified genes which may be partially responsible for the development of cerebral palsy.
Mar 29, 2024
0
49
Regulators of gene expression are thought to play an outsized role in disorders from cancers to heart disease. But how exactly do variations in gene regulation translate into a disease's biology?
Mar 28, 2024
0
19
Researchers at the University of Cambridge have created the world's largest catalogue of human breast cells, which has revealed early cell changes in healthy carriers of BRCA1 and BRCA2 gene mutations.
Mar 28, 2024
0
66
Cancer cells are characterized by their aggressiveness: they grow rapidly and spread to other parts of the body. To enable this, numerous mechanisms come into play, and one of them involves a protein called MYC, which activates ...
Mar 7, 2024
0
34
In the largest genome-wide association study to date on type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated ...
Feb 19, 2024
0
38
New research led by a team of scientists from Queen's University Belfast and the Cancer Research UK (CRUK) Scotland Institute in Glasgow have made a series of groundbreaking discoveries into tumor biology that may be used ...
Feb 13, 2024
0
15
Whether we stay healthy or become seriously ill is determined by our genes. But also, the folding of our genome has a significant influence on this, as the 3D genome organization regulates which genes are switched on and ...
Jan 30, 2024
0
37
A new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease. The tool, described in a new paper published January 26, 2024, in Nature Genetics, ...
Jan 26, 2024
0
45
