Nature Reviews Drug Discovery

Alzheimer's disease & dementia

Preventive treatment for Alzheimer's and Parkinson's disease

A diagnosis of Alzheimer's disease is devastating for those affected, as there is still no cure for this type of dementia. One hundred years after Alois Alzheimer first described it, we neither have a drug for it, nor do ...

Medications

Characteristics of international drug regulatory regimes

The regulatory requirements for the approval of new drugs vary greatly internationally in regards to the resources allocated to the authorities, the evaluation periods for approval and the fees for the pharmaceutical companies. ...

Medications

New research predicts market share for drug makers

Lagging behind in launching new medicines means a much smaller market share for pharmaceutical companies—even if they spend just as much on advertising, according to new research from Duke University's Fuqua School of Business.

Medications

Drug research and development more efficient than expected

Drug R&D costs have increased substantially in recent decades, while the number of new drugs has remained fairly constant, leading to concerns about the sustainability of drug R&D and question about the factors that could ...

Alzheimer's disease & dementia

Potential Alzheimer's drug prevents abnormal blood clots in the brain

Without a steady supply of blood, neurons can't work. That's why one of the culprits behind Alzheimer's disease is believed to be the persistent blood clots that often form in the brains of Alzheimer's patients, contributing ...

Medications

Targeting drugs to reduce side effects

(Medical Xpress)—Consider ice cream – the base of which is frozen cream. Ingredients are then added to make different flavours. All these flavours are distinctly different but are created from the same foundation.

page 2 from 3