Oncogene

Medical research

Sugar chains on cell surfaces direct cancer cells to die

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, ...

Oncology & Cancer

The mechanisms behind cancer cell resistance to TRAIL treatment

Researchers at KoƧ University discovered why a promising class of cancer treatments fail, and their findings point to how such treatments might be made to work. The research revealed the mechanisms behind the development ...

Oncology & Cancer

New discovery enhances understanding of colorectal cancer

MUSC Hollings Cancer Center researchers discovered a novel mechanism showing how a certain gene mutation can allow tumors to evade detection by the immune system in colorectal cancer patients. The study, which was published ...

Oncology & Cancer

Melanoma of the eye: Preclinical tests show path toward treatment

Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new ...

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